MODERN ADVANCES AND EXPANDING APPLICATIONS OF BIOPHYSICS IN MEDICINE, BIOTECHNOLOGY, AND COMPUTATIONAL SCIENCES
Keywords:
Biophysics; Molecular biophysics; Medical physics; Nanobiophysics; Computational modeling; Biomedical engineering; Artificial intelligence in medicine; Radiation biophysics; Biosensors; ElectrophysiologyAbstract
Biophysics has evolved into a highly interdisciplinary scientific field that integrates principles of physics, biology, mathematics, and computational modeling to investigate the structure and function of living systems. In recent decades, rapid technological development has significantly expanded the applications of biophysics across medicine, biotechnology, molecular biology, and artificial intelligence–based diagnostics. The present study provides a comprehensive analysis of modern advances in biophysics, focusing on molecular biophysics, cellular electrophysiology, medical imaging physics, radiation biophysics, nanobiophysics, and computational biophysical modeling.
A systematic analytical approach was employed to evaluate contemporary scientific contributions and emerging technologies within these domains. Particular attention was given to the integration of machine learning algorithms, high-resolution imaging systems, biosensor technologies, and simulation-based modeling in clinical and experimental settings.
References
1.Alberts B, Johnson A, Lewis J, Morgan D, Raff M, Roberts K, Walter P. Molecular Biology of the Cell. 7th ed. Garland Science; 2022.
2.Bialek W. Biophysics: Searching for Principles. Princeton University Press; 2012.
3.Nelson P. Biological Physics: Energy, Information, Life. 2nd ed. W.H. Freeman; 2020.
4.Phillips R, Kondev J, Theriot J, Garcia H. Physical Biology of the Cell. 2nd ed. Garland Science; 2012.
5.Hille B. Ion Channels of Excitable Membranes. 3rd ed. Sinauer Associates; 2001.
6.Koch C. Biophysics of Computation: Information Processing in Single Neurons. Oxford University Press; 2004.
7.Seifert U. Stochastic thermodynamics and molecular systems. Rep Prog Phys. 2012;75(12):126001.
8.Wang Y, Wang Y. Nanotechnology applications in biomedical engineering. J Biomed Nanotechnol. 2018;14(1):1–18.
9.Sackmann E. Biological membrane structure and function. In: Lipowsky R, Sackmann E, editors. Structure and Dynamics of Membranes. Elsevier; 1995. p.1–63.
10.Hofmann H, Soranno A, Borgia A. Polymer scaling laws of unfolded proteins. Proc Natl Acad Sci USA. 2012;109(40):16155–16160.
11.Akhmedova DI, Ashurova DT. Influence of integrated preventive approaches on physiological development indicators in children. Pediatriya (Tashkent). 2012;(3–4):3–4.
12.Ishniyazova ND, Salikhova GU, Akhmedova DI. Physiological and biochemical indicators in pediatric populations. Pediatriya (Tashkent). 2012;(3–4):3–4.
13.Sadirkhodzhaeva AA, Ashurova DT. Early diagnostic markers of cardiovascular dysfunction in pediatric diabetes. Austrian Journal of Technical and Natural Sciences. 2019:3–7.
14.Sadirkhodzhaeva AA. Hemostasis parameters and endothelial dysfunction in children with type 1 diabetes. Medical Journal of Uzbekistan. 2025:150–154.
15.Sadirkhodzhaeva AA, Ashurova DT. hs-CRP as a marker of vascular inflammation in pediatric diabetes. Young Scientists in Medicine. 2022:109–113.
