CLINICAL AND LABORATORY PARAMETERS AND THEIR RELATIONSHIP WITH THE LEVEL OF MAGNESIUM IN OSTEOARTHRITIS AGAINST THE BACKGROUND OF UNDIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA

Authors

  • Akhmedzhanova Diyora Marufovna Assistant of the Department of Physiology, Pathophysiology, Pharmacology, Hygiene, Chemistry University of Zarmed Samarkand, Uzbekistan Author

Keywords:

Osteoarthritis, undifferentiated connective tissue dysplasia, magnesium ions (Mg2+), autoantibodies to type I collagen.

Abstract

The purpose of this work is to conduct a comparative analysis of the parameters of antibodies to type I collagen and their relationship with Mg2+ ions in patients with osteoarthritis against the background of undifferentiated connective tissue dysplasia (UCTD). The study involved 88 individuals aged 25 to 55 (35.2±1.89) years with phenotypic signs of UCTD and osteoarthritis. In patients with osteoarthritis against the background of UCTD, there was a decrease in the level of Mg2+ ions and an increase in titers of autoantibodies to type I collagen. The dynamics of changes in the level of autoantibodies, as well as magnesium, depending on the severity of the clinical course of osteoarthritis against the background of UCTD, can serve as a method for assessing the progression of the pathological process and prognosis of the disease.

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Published

2025-05-24

Issue

Vol. 1 No. 2 (2025)

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

CLINICAL AND LABORATORY PARAMETERS AND THEIR RELATIONSHIP WITH THE LEVEL OF MAGNESIUM IN OSTEOARTHRITIS AGAINST THE BACKGROUND OF UNDIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA. (2025). Modern American Journal of Medical and Health Sciences, 1(2), 143-148. https://usajournals.org/index.php/1/article/view/186