THE ROLE OF OPTICAL COHERENCE TOMOGRAPHY IN THE EARLY DETECTION OF GLAUCOMA AND AGE-RELATED MACULAR DEGENERATION
Keywords:
Optical coherence tomography, glaucoma, age-related macular degeneration, retinal nerve fiber layer, ganglion cell complex, macula, early diagnosis, OCT angiography.Abstract
Optical coherence tomography (OCT) is a modern, non-invasive diagnostic modality in ophthalmology that enables high-resolution cross-sectional imaging of ocular tissues. This article provides a comprehensive analysis of the role of OCT in the early detection of glaucoma and age-related macular degeneration (AMD), highlighting its capabilities, advantages, and clinical significance.
References
1.Tham YC, Li X, Wong TY, Quigley HA, Aung T, Cheng CY. Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis. Ophthalmology. 2014;121(11):2081-90.
2. Mitchell P, Liew G, Gopinath B, Wong TY. Age-related macular degeneration. Lancet. 2018;392(10153):1147-59.
3. Weinreb RN, Aung T, Medeiros FA. The pathophysiology and treatment of glaucoma: a review. JAMA. 2014;311(18):1901-11.
4. Schuster AK, Erb C, Hoffmann EM, et al. The diagnosis and treatment of glaucoma. Dtsch Arztebl Int. 2020;117:225-34.
5. Grzybowski A, Och M, Kanclerz P, et al. Primary open angle glaucoma and vascular risk factors: a review of population based studies from 1990 to 2019. J Clin Med. 2020;9:761.
6. Sun X, Dai Y, Chen Y, et al. Primary angle closure glaucoma: what we know and what we don‘t know. Prog Retin Eye Res. 2017;57:26-45.
7. Holz FG, Sadda SR, Staurenghi G, et al. Imaging protocols in age-related macular degeneration. Ophthalmology. 2017;124(4):544-56.
8. Huang D, Swanson EA, Lin CP, et al. Optical coherence tomography. Science. 1991;254(5035):1178-81.
9. Fujimoto JG, Pitris C, Boppart SA, Brezinski ME. Optical coherence tomography: an emerging technology for biomedical imaging and optical biopsy. Neoplasia. 2000;2(1-2):9-25.
10. Drexler W, Fujimoto JG. State-of-the-art retinal optical coherence tomography. Prog Retin Eye Res. 2008;27(1):45-88.
11. Dong ZM, Wollstein G, Schuman JS. Clinical utility of optical coherence tomography in glaucoma. Invest Ophthalmol Vis Sci. 2016;57(9):OCT556-67.
12. Lains I, Wang JC, Cui Y, et al. Retinal applications of swept source optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA). Prog Retin Eye Res. 2021;84:100951.
13. Rothenbuehler SP, Malmqvist L, Belmouhand M, et al. Comparison of spectral-domain OCT versus swept-source OCT for the detection of deep optic disc drusen. Diagnostics (Basel). 2022;12(10):2515.
14. Spaide RF, Fujimoto JG, Waheed NK, Sadda SR, Staurenghi G. Optical coherence tomography angiography. Prog Retin Eye Res. 2018;64:1-55.
15. Campbell JP, Zhang M, Hwang TS, et al. Detailed vascular anatomy of the human retina by projection-resolved optical coherence tomography angiography. Sci Rep. 2017;7(1):42201.
16. Kolb H. Simple anatomy of the retina. Webvision. 2012.
