MODERN CONCEPTS OF PATHOGENETIC MECHANISMS OF OVARIAN DYSFUNCTION

Authors

  • Azizova Z. Sh. Institute of Immunology and Human Genomics, Academy of Sciences of the Republic of Uzbekistan Author
  • Musakhodzhaeva D.A. Institute of Immunology and Human Genomics, Academy of Sciences of the Republic of Uzbekistan Author
  • Mukhamedov R. S. Hayot Technology LLC Author
  • Ruzimuradov N. F. Institute of Immunology and Human Genomics, Academy of Sciences of the Republic of Uzbekistan Author
  • Rustamova N. B. Institute of Immunology and Human Genomics, Academy of Sciences of the Republic of Uzbekistan Author
  • Mannopjonov P. B. Institute of Immunology and Human Genomics, Academy of Sciences of the Republic of Uzbekistan Author

Keywords:

ovarian dysfunction, pathogenesis, immune mechanisms, neuroendocrine regulation, cytokines, polycystic ovary syndrome, ovarian reserve, diagnostics, inflammation, reproductive function.

Abstract

Ovarian dysfunction is a complex functional disorder driven by interactions among neuroendocrine, immune, metabolic, and genetic factors. This review article presents contemporary concepts of the pathogenetic mechanisms underlying ovarian dysfunction, emphasizing the role of cytokines, disturbances in hypothalamic-pituitary-ovarian axis regulation, and immune and genetic determinants. Special attention is given to diagnostic approaches and interdisciplinary aspects of patient management. The review is based on the analysis of recent data from authoritative international sources.

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Published

2025-05-03

Issue

Vol. 1 No. 1 (2025)

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

MODERN CONCEPTS OF PATHOGENETIC MECHANISMS OF OVARIAN DYSFUNCTION. (2025). Modern American Journal of Medical and Health Sciences, 1(1), 36-50. https://usajournals.org/index.php/1/article/view/31