COMPARATIVE ASSESSMENT OF MORPHOLOGICAL AND MICROCIRCULATORY CHANGES IN THE THYMUS OF WHITE RATS IN ALIMENTARY ZINC (ZN) MICROELEMENTOSIS

Authors

  • Turdiev M. R. Bukhara State Medical Institute Named Abu Ali ibn Sina, Bukhara City, Uzbekistan Author
  • Teshaev Sh. J. Bukhara State Medical Institute Named Abu Ali ibn Sina, Bukhara City, Uzbekistan Author

Keywords:

Zinc deficiency, thymus, white rat, T-lymphocytes, immune system.The actual ministry.

Abstract

In this study, a comparative analysis of morphological and microcirculatory changes in the thymus of white rats with alimentary zinc (Zn) deficiency was conducted. During the experiment, dynamic changes in the lymphoid structures of the thymus, the degree of differentiation of thymocytes, the cortico-medullary ratio, and the reaction of stromal elements were morphometrically assessed. Disorders of parenchymal-stromal balance of the thymus, morphometric indicators of lymphoid tissue, a decrease in the number of lymphoid cells, as well as an increase in the thickness of the vessel wall and a decrease in the internal diameter of the organ were revealed. The obtained results highlight the important role of zinc in immunohomeostasis and create a scientific basis for a broader understanding of the immunopathological mechanisms of microelementoses.

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Published

2025-12-02

Issue

Vol. 1 No. 8 (2025)

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

COMPARATIVE ASSESSMENT OF MORPHOLOGICAL AND MICROCIRCULATORY CHANGES IN THE THYMUS OF WHITE RATS IN ALIMENTARY ZINC (ZN) MICROELEMENTOSIS. (2025). Modern American Journal of Medical and Health Sciences, 1(8), 269-278. https://usajournals.org/index.php/1/article/view/1477